The use of animals in drug safety assessments is not yet replaceable by computational methods and is required by regulatory bodies.  Control groups are part of the scientific method to assess drug safety. We are exploring the ability to provide better statistical power and reduce animal usage by using control group information selected from past studies to assess the control baseline.  Data from control groups selected from past studies with the same routes of administration, duration, species, and strain are being compared to normal control groups to evaluate their performance. Join us for the third webinar in the Life Science webinar series to learn more.
Matthew Clark, Ph.D
Global Head of Science Analytics, Charles River Laboratories
Matthew Clark, Ph. D.  is Global Head of Science Analytics at Charles River Laboratories.  In this role he explores ways to implement analytics, AI, and data science across the organization with a particular focus on improving the efficiency of safety assessment.  Dr. Clark was previously Director of Scientific Services at Elsevier, leading a global team providing data analytics services for life sciences and other organizations.  He also has over a decade of experience in pharmaceutical discovery and development.
Michelle Mohsenin RPh
Product Manager, Embase
Michelle Mohsenin Rph is a Product Manager for Elsevier supporting the biomedical journal database, Embase as a Drug Safety/Pharmacovigilance Subject Matter Expert. Prior to Elsevier she was Senior Drug Safety Officer for Pfizer where she led the Global Literature Surveillance group. She was responsible for being regulation compliance to ensure inspection readiness.  She is a licensed New Jersey pharmacist.

Thomas Vargues
Product Manager, Pharmapendium
Thomas Vargues is currently Product Manager of PharmaPendium, an Elsevier digital platform specialized in regulatory information to help drugs development for the pharmaceutical industry. Thomas previous role within Elsevier was program manager where he was responsible to build value-based projects for chemical researchers support. Thomas was working for Schlumberger where he was a reservoir engineer working for the Engineering and Development Department. He was responsible for the design of New Chemical Fluid Technologies in the laboratory and supervising its implementation on offshore fields. Thomas holds a PhD in Biochemistry from the Edinburgh University (2005-2009) and worked as a postdoctoral associate at King’s College London (2010).
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