About
In recognition of National Diabetes Month, join us for an enlightening webinar that delves into the complexities of diabetes management and research. This session will focus on the intricate interplay between bioactive compounds and their off-target effects, with a special emphasis on the enzyme Stearoyl-CoA 9-desaturase (SCD).

Diabetes mellitus is a multifaceted metabolic disorder characterized by chronic hyperglycemia, which poses significant health challenges worldwide. This webinar aims to delve into the intricate relationship between diabetes management and the biochemical pathways involved, with a particular focus on off-target effects, bioactivity, and the pivotal enzyme Stearoyl-CoA 9-desaturase (SCD1).

We will begin by examining the role of SCD1 in lipid metabolism and its implications for insulin sensitivity and glucose homeostasis. Studies suggest that modulation of SCD1 activity can influence the bioactivity of various pharmacological agents used in diabetes treatment, potentially leading to unintended off-target effects. Utilizing Embiology and Reaxys, we will analyze the chemical interactions and biological pathways associated with SCD1, highlighting its significance in drug design and therapeutic strategies.

The webinar will also cover the latest research findings on the bioactivity of compounds targeting SCD1, assessing their efficacy and safety profiles. We will discuss how understanding these interactions can aid in minimizing off-target effects, thereby optimizing diabetes treatments and improving patient outcomes.

Join us for an insightful session that integrates biochemical insights with practical applications in diabetes management, fostering a comprehensive understanding of how targeted therapies can be refined through the study of off-target effects and enzyme activity. Attendees will leave with how Elsevier Life Science Solutions can drive innovative approaches to enhance therapeutic efficacy while reducing adverse effects.
Presenters
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Derrick Umali
Life Sciences Account Manager, Elsevier
Derrick Umali has worked with life science customers in the Academic/Government and Corporate space for over 20 years. He started at MDL-Elsevier supporting cheminformatic and bioinformatics solutions – first as customer support and then moving to field application scientist role.

Currently, he is working with Americas Academic and Government Team to support Elsevier’s Life Science Portfolio.
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Kriston Waterman
Americas Life Science Account Manager, Elsevier
Kriston Waterman has worked in Healthcare for over a decade and was responsible for Cloud based, IoT hardware, medical devices, and professional services solutions that primarily targeted large Healthcare Provider systems and Life Science organizations.

Currently, he is working with the Americas Academic and Government Team to support Elsevier’s Life Science Portfolio.
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Scott Newman
Americas Customer Consultant Life Sciences , Corporate, Elsevier
Scott is a seasoned research professional with blended experience in the biotech/pharmaceutical fields. His focus is on helping scientists and their organization understand how to use the scientific, chemical and computational databases to achieve success. He has spent time as a team leader with Xenon Pharma. He received his PhD in Botany from University of Washington and did his NIH postdoc at Duke University.

Currently, he is working with Americas Corporate to support Elsevier’s Life Science Portfolio.
S
Sheena Shah
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